Schutz, JDS, de Azambuja CB, Cunha GR, Cavagni J, Rosing CK, Haas AN, Thome FS, Fiorini T.
2020.
Association between severe periodontitis and chronic kidney disease severity in predialytic patients: A cross-sectional study, Mar. Oral Dis. 26:447-456., Number 2
AbstractOBJECTIVE: The aim of this cross-sectional study was to evaluate the association between periodontitis and different severities of chronic kidney disease (CKD) in predialytic patients. MATERIALS AND METHODS: Demographic, socioeconomic, and medical data of 139 patients from the nephrology service of one university hospital in Porto Alegre, Brazil, were obtained through interview and clinical records. Full-mouth six-sites per tooth periodontal examinations were performed. Associations between periodontitis, stages of CKD, and estimated glomerular filtration rate (eGFR) were estimated by multivariable models adjusted for sex, smoking, vitamin D supplementation, physical activity, and renal treatment duration. CKD was classified based on eGFR (<60 ml/min/1.73 m(2) ) estimated by the Chronic Kidney Disease Epidemiology Collaboration equation. RESULTS: Patients with severe periodontitis, compared to those without severe periodontitis, had 2.8 (95% CI: 1.25-6.62) and 3.4 (95% CI: 1.27-9.09) times higher risk of being in stages 4 and 5 of CKD, respectively. Having >/= 2 teeth with clinical attachment loss (CAL) >/=6 mm increased 3.9 times the risk of being in stage 5 of CKD. Patients with severe periodontitis and >/=2 teeth with CAL >/= 6 mm had 4.4 ml/min/1.73(2) and 5.2 ml/min/1.73(2) lower eGFR (p-values < .05), respectively. CONCLUSION: Severe periodontitis was associated with poor renal conditions in predialytic CKD patients, strengthening the importance of periodontal evaluation in such patient population.
Frozza, CF, Pivel MAG, Suárez-Ibarra JY, Ritter MN, Coimbra JC.
2020.
Bioerosion on late Quaternary planktonic Foraminifera related to paleoproductivity in the western South Atlantic, 2020. Paleoceanography and PaleoclimatologyPaleoceanography and Paleoclimatology. n/a(n/a):e2020PA003865.: John Wiley & Sons, Ltd
AbstractKey Points: For the first time, drill holes in planktonic Foraminifera from the western South Atlantic were compared with paleoceanographic proxies. Paleoproductivity of the western South Atlantic was reconstructed using assemblage and geochemical indexes for the last 46 kyr. Paleoproductivity estimates and bioerosion rates of planktonic foraminiferal tests show a strong relation during late Quaternary.
Redondo, J, Popik B, Casagrande M, Silva M, Quillfeldt JA, De Oliveira Alvares L, Mello e Souza T.
2020.
HECT E3 ligase inhibition facilitates consolidation, retrieval, and reconsolidation, and inhibits extinction of contextual fear memory. Neurobiology of Learning and memory.