<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pinto, Jpns</style></author><author><style face="normal" font="default" size="100%">Goergen, J.</style></author><author><style face="normal" font="default" size="100%">Muniz, Fwmg</style></author><author><style face="normal" font="default" size="100%">Haas, A. N.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Vitamin D levels and risk for periodontal disease: A systematic review</style></title><secondary-title><style face="normal" font="default" size="100%">J Periodontal Res</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Databases, Factual</style></keyword><keyword><style  face="normal" font="default" size="100%">Dietary Supplements</style></keyword><keyword><style  face="normal" font="default" size="100%">epidemiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">periodontal disease</style></keyword><keyword><style  face="normal" font="default" size="100%">Periodontal Diseases/*blood/epidemiology/etiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Randomized Controlled Trials as Topic</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk Factors</style></keyword><keyword><style  face="normal" font="default" size="100%">systematic review</style></keyword><keyword><style  face="normal" font="default" size="100%">vitamin D</style></keyword><keyword><style  face="normal" font="default" size="100%">Vitamin D/administration &amp; dosage/*blood</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Jun</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/29492977</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">3</style></number><edition><style face="normal" font="default" size="100%">2018/03/02</style></edition><volume><style face="normal" font="default" size="100%">53</style></volume><pages><style face="normal" font="default" size="100%">298-305</style></pages><isbn><style face="normal" font="default" size="100%">1600-0765 (Electronic)0022-3484 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;OBJECTIVE: To evaluate the existing evidence supporting or refuting the following questions: (i) Do patients with lower vitamin D levels have higher risk for periodontal disease? (ii) Are periodontal treatment outcomes improved by the adjuvant supplementation of vitamin D or by elevated serum vitamin D levels? MATERIAL AND METHODS: MEDLINE, SCOPUS, EMBASE and Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched up to September 2017. Studies were included if they had measured serum vitamin D levels or vitamin D intake and any periodontal parameter. RESULTS: Overall, 27 studies were included (13 cross-sectional studies, 6 case-control studies, 5 cohort studies, 2 randomized clinical trials and 1 case series study). Sixty-five percent of the cross-sectional studies reported significant associations between low vitamin D levels and poor periodontal parameters. None of the observational longitudinal studies found that periodontal disease progression could be attributed to lower vitamin D levels. No interventional studies that evaluated the use of vitamin D supplementation as a solely adjuvant to periodontal treatment was found. No meta-analysis was performed due to high variability across studies. CONCLUSION: The data to support or refute the association between vitamin D levels and periodontal disease are inconclusive at the moment. More rigorously designed longitudinal studies with standardized definitions of periodontal disease and vitamin D are necessary.&lt;/p&gt;
</style></abstract><accession-num><style face="normal" font="default" size="100%">29492977</style></accession-num><notes><style face="normal" font="default" size="100%">&lt;p&gt;Pinto, J P N SGoergen, JMuniz, F W M GHaas, A NengSystematic ReviewJ Periodontal Res. 2018 Jun;53(3):298-305. doi: 10.1111/jre.12531. Epub 2018 Mar 1.&lt;/p&gt;
</style></notes><auth-address><style face="normal" font="default" size="100%">Periodontology, Faculty of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.</style></auth-address></record></records></xml>