<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Haas, A. N.</style></author><author><style face="normal" font="default" size="100%">Silva-Boghossian, C. M.</style></author><author><style face="normal" font="default" size="100%">Colombo, A. P.</style></author><author><style face="normal" font="default" size="100%">Albandar, J.</style></author><author><style face="normal" font="default" size="100%">Oppermann, R. V.</style></author><author><style face="normal" font="default" size="100%">Rosing, C. K.</style></author><author><style face="normal" font="default" size="100%">Susin, C.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Predictors of clinical outcomes after periodontal treatment of aggressive periodontitis: 12-month randomized trial</style></title><secondary-title><style face="normal" font="default" size="100%">Braz Oral Res</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adolescent</style></keyword><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Aggressive Periodontitis/*therapy</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-Bacterial Agents/therapeutic use</style></keyword><keyword><style  face="normal" font="default" size="100%">Azithromycin/therapeutic use</style></keyword><keyword><style  face="normal" font="default" size="100%">Dental Plaque/microbiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Dental Scaling/*methods</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Multivariate Analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Oral Hygiene/*methods</style></keyword><keyword><style  face="normal" font="default" size="100%">Periodontal Index</style></keyword><keyword><style  face="normal" font="default" size="100%">Periodontium/microbiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Root Planing/*methods</style></keyword><keyword><style  face="normal" font="default" size="100%">Time Factors</style></keyword><keyword><style  face="normal" font="default" size="100%">Treatment Outcome</style></keyword><keyword><style  face="normal" font="default" size="100%">Young Adult</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 20</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/27223128</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">1</style></number><edition><style face="normal" font="default" size="100%">2016/05/26</style></edition><volume><style face="normal" font="default" size="100%">30</style></volume><isbn><style face="normal" font="default" size="100%">1807-3107 (Electronic)1806-8324 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Little is known about the factors that may be used in clinical practice to predict the therapeutic response of aggressive periodontitis patients. The aim of this study was to determine predictors of clinical outcomes after non-surgical treatment of aggressive periodontitis. A total of 24 patients (aged 13-26 years) received oral hygiene instructions, as well as subgingival scaling and root planing. Twelve subjects received systemic azithromycin at random. Clinical variables were assessed at baseline, 3, 6, 9, and 12 months. Baseline microbiological assessment was performed by checkerboard DNA-DNA hybridization. Multivariable models used generalized estimating equations. There were significant improvements in the entire sample in regard to pocket depth, clinical attachment level and bleeding on probing. Significant predictors of a reduction in mean pocket depth were: use of azithromycin, non-molar teeth, generalized disease and baseline pocket depth. Absence of plaque predicted a 0.22 mm higher attachment gain, whereas a baseline pocket depth &amp;gt;/=7 mm predicted a 1.36 mm higher attachment loss. Azithromycin, plaque, and baseline pocket depth were significant predictors of bleeding on probing. The concomitant presence of all three red complex species predicted a 0.78 mm higher attachment loss. It may be concluded that dental plaque, tooth type, disease extent, baseline pocket depth, and use of azithromycin were significant predictors of the clinical response to treatment for aggressive periodontitis in young individuals. Moreover, the presence of multiple periodontal pathogens may predict challenges in achieving a favorable outcome for aggressive periodontitis.&lt;/p&gt;
</style></abstract><accession-num><style face="normal" font="default" size="100%">27223128</style></accession-num><notes><style face="normal" font="default" size="100%">&lt;p&gt;Haas, Alex NogueiraSilva-Boghossian, Carina MacielColombo, Ana PaulaAlbandar, JasimOppermann, Rui VicenteRosing, Cassiano KuchenbeckerSusin, CristianoengRandomized Controlled TrialBrazilBraz Oral Res. 2016 May 20;30(1). pii: S1806-83242016000100245. doi: 10.1590/1807-3107BOR-2016.vol30.0041.&lt;/p&gt;
</style></notes><auth-address><style face="normal" font="default" size="100%">Universidade Federal do Rio Grande do Sul, Faculty of Dentistry, Periodontology, Porto Alegre, Brazil.Universidade Federal do Rio de Janeiro - UFRJ, Institute of Microbiology, Rio de Janeiro, RJ, Brazil.Temple University, School of Dentistry, Department of Periodontology, Philadelphia, PA, USA.Georgia Regents University, Departments of Periodontics and Oral Biology, Augusta, GA, USA.</style></auth-address></record></records></xml>