@article {721,
	title = {Association among menopause, hormone replacement therapy, and periodontal attachment loss in southern Brazilian women},
	journal = {J Periodontol},
	volume = {80},
	number = {9},
	year = {2009},
	note = {<p>Haas, Alex NRosing, Cassiano KOppermann, Rui VAlbandar, Jasim MSusin, CristianoengComparative StudyResearch Support, Non-U.S. Gov{\textquoteright}t2009/09/03 06:00J Periodontol. 2009 Sep;80(9):1380-7. doi: 10.1902/jop.2009.090082.</p>
},
	month = {Sep},
	pages = {1380-7},
	abstract = {<p>BACKGROUND: The aim of the present study was to evaluate the association among menopause, hormone replacement therapy (HRT), and periodontal attachment loss (PAL). METHODS: Three hundred twenty-eight women (40 to 69 years old) who participated in a previous oral survey in South Brazil were included. Women who reported not having their monthly menstrual cycles for \&gt;or=12 months were classified as postmenopausal. Postmenopausal women were categorized according to HRT. Women with \&gt;or=30\% teeth with PAL \&gt;or=5 mm were classified as having periodontitis. The data were analyzed using a multivariable logistic regression model and adjusted for age, smoking, socioeconomic status, and dental care. RESULTS: The prevalence of periodontitis was significantly greater among postmenopausal women not using HRT (HRT-) than among premenopausal women (64.4\% versus 46.3\%; P = 0.005). Similarly, the multivariable analysis demonstrated a significantly higher chance of having periodontitis in postmenopausal HRT- women than in premenopausal women (odds ratio [OR], 2.1; 95\% confidence interval [CI]: 1.1 to 4.0). In contrast, no significant differences were observed in the prevalence of periodontitis between postmenopausal women using HRT (HRT+) and premenopausal women (48.8\% versus 46.3\%; P = 0.77). After adjusting for cofactors, postmenopausal HRT+ women did not have a greater likelihood of having periodontitis than premenopausal women (OR, 1.2; 95\% CI: 0.6 to 2.5). No significant differences in tooth loss were observed among the study groups after adjusting for confounders. CONCLUSIONS: Postmenopausal HRT- women had a greater chance of having periodontitis than premenopausal women. In contrast, postmenopausal HRT+ women and premenopausal women had similar periodontal status. HRT may have a beneficial effect on periodontal health.</p>
},
	keywords = {*Estrogen Replacement Therapy, Adult, Age Factors, Aged, Brazil, Dental Care, Female, Humans, Menopause/*physiology, Middle Aged, Periodontal Attachment Loss/*etiology, Periodontitis/etiology, Postmenopause/drug effects/physiology, Premenopause/physiology, Risk Factors, Smoking, Social Class, Tooth Loss/etiology},
	isbn = {0022-3492 (Print)0022-3492 (Linking)},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/19722786},
	author = {Haas, A. N. and Rosing, C. K. and Oppermann, R. V. and Albandar, J. M. and Susin, C.}
}
