@article {6610,
	title = {Association between severe periodontitis and chronic kidney disease severity in predialytic patients: A cross-sectional study},
	journal = {Oral Dis},
	volume = {26},
	number = {2},
	year = {2020},
	note = {<p>Schutz, Jasper da Silvade Azambuja, Carolina BarreraCunha, Giuliano ReolonCavagni, JulianoRosing, Cassiano KuchenbeckerHaas, Alex NogueiraThome, Fernando SaldanhaFiorini, Tiagoeng150319/Hospital de Clinicas de Porto Alegre160428/Hospital de Clinicas de Porto AlegreDenmarkOral Dis. 2020 Mar;26(2):447-456. doi: 10.1111/odi.13236. Epub 2019 Dec 5.</p>
},
	month = {Mar},
	pages = {447-456},
	edition = {2019/11/20},
	abstract = {<p>OBJECTIVE: The aim of this cross-sectional study was to evaluate the association between periodontitis and different severities of chronic kidney disease (CKD) in predialytic patients. MATERIALS AND METHODS: Demographic, socioeconomic, and medical data of 139 patients from the nephrology service of one university hospital in Porto Alegre, Brazil, were obtained through interview and clinical records. Full-mouth six-sites per tooth periodontal examinations were performed. Associations between periodontitis, stages of CKD, and estimated glomerular filtration rate (eGFR) were estimated by multivariable models adjusted for sex, smoking, vitamin D supplementation, physical activity, and renal treatment duration. CKD was classified based on eGFR (\&lt;60 ml/min/1.73 m(2) ) estimated by the Chronic Kidney Disease Epidemiology Collaboration equation. RESULTS: Patients with severe periodontitis, compared to those without severe periodontitis, had 2.8 (95\% CI: 1.25-6.62) and 3.4 (95\% CI: 1.27-9.09) times higher risk of being in stages 4 and 5 of CKD, respectively. Having \&gt;/= 2 teeth with clinical attachment loss (CAL) \&gt;/=6 mm increased 3.9 times the risk of being in stage 5 of CKD. Patients with severe periodontitis and \&gt;/=2 teeth with CAL \&gt;/= 6 mm had 4.4 ml/min/1.73(2) and 5.2 ml/min/1.73(2) lower eGFR (p-values \&lt; .05), respectively. CONCLUSION: Severe periodontitis was associated with poor renal conditions in predialytic CKD patients, strengthening the importance of periodontal evaluation in such patient population.</p>
},
	keywords = {Adult, Aged, Brazil, chronic kidney disease, chronic renal insufficiency, Cross-Sectional Studies, Female, Glomerular Filtration Rate, Humans, Male, Middle Aged, periodontitis, Periodontitis/*complications, Renal Insufficiency, Chronic/*complications, Risk Factors, Young Adult},
	isbn = {1601-0825 (Electronic)1354-523X (Linking)},
	url = {https://www.ncbi.nlm.nih.gov/pubmed/31742816},
	author = {Schutz, J. D. S. and de Azambuja, C. B. and Cunha, G. R. and Cavagni, J. and Rosing, C. K. and Haas, A. N. and Thome, F. S. and Fiorini, T.}
}
